JeanMarie Guenot And Amphivena Therapeutics: Chasing The Cure For Cancer

 

It has been an exciting year for Amphivena Threrapeutics. The company developed several promising advances in cancer immunotherapies. One of the most notable of these is AMV564, the company’s proprietary T-cell redirecting bispecific CD33/CD3 antibody. The United States Fod and Drug Administration accepted the investigational drug and it will began to be given to Leukemia patients.

 

While AMV564 is only in phase one of the investigational process, Jeanmarie Guenot, Ph.D., the president and chief executive officer of Amphivena Therapeutics (http://amphivena.com/amphivena_leaders/jeanmarie-guenot-ph-d/), is positive that it will bring promising news to the pharmaceutical industry. She believes that this first phase will open several new treatment options for medical professionals and cancer patients.

 

“Our preclinical program demonstrated impressive cytotoxic activity in AML patient samples and animal models that was both potent and selective,” Guenot explained. “This is suggesting the potential for a robust therapeutic response with minimal off-target safety concerns.”

 

Guenot looks forward to beginning the clinical phase of testing and is optimistic about the future of Amphivena Therapeutics. The company believes that this therapy treatment has huge potential to change the way cancer is approached.

 

JeanMarie Guenot further explains on her personal Facebook, that AMV564 aims to eliminate cancer cells in the body, including the bine, marrow and blood. If phase one goes as plan, AMV564 could be headed to clinical trials very soon.

 

Guenot is no stranger to this industry. In fact, she has more than twenty years in the pharmaceutical and biotechnology industry. Her leadership of the San Francisco based, Amphivena Therapeutics has been a highlight of her career. With such promising advancement being made, Guenot and Amphivena Therapeutics have been featured by several major news outlets, such as BusinessWire.

 

The future looks extremely bright for this successful oncology startup company whose mission is to eliminate the presence of blood cancers and provided a cure to those it has affected.  Jeanmarie Guenot and Amphivena announced a partnership with Takeda to continue their medical work.

 

The Story of SweetGreen

The story of Sweetgreen begins with Nathaniel Ru and his friends having trouble finding healthy places to eat while in college. In addition to healthy they were looking for restaurants that were “fun and easy”. To this end they took particular interest in a nearby tavern which they transformed into the founding location of the Sweetgreen chain of restaurants.

Six years later, they had rebuilt the tavern, located in Washington D.C., into a 21-store-farm-to-table restaurant. The landlord of the building that the tavern was located in had doubts about their plans, but eventually they were able to convince her to lease the location to them. From that one location Sweetgreen has now expanded to restaurants across the nation including the states of New York, Massachusetts, Pennsylvania, and the greater Washington D.C. area.

The food that the company uses mostly comes from local farmers around each restaurant location. In addition to offering food, Sweetgreen’s Head of Digital Marketing Theresa Dold has stated that the company was started with a “deeper purpose”. This purpose was for Sweetgreen to answer the question of “why”. She went on to say that they want to be local, smart, sexy, and social and by the way we sell a great line of juices and have a music festival every year.

Nathaniel Ru has stated that every restaurant they open has to live up to their five core values which includes serving the local community around it. The core values include “win, win, win” where everyone has a stake, sustainability, “keeping it real” where everything is authentic, “sweet” which means creating meaningful connections between farmers, Sweetgreen, and customers, and making a positive impact.

As the company wants to connect food and music, they came up with a food & musical festival that they called Sweetlife. Sweetlife has evolved into the areas largest music and food festival, with as many as 20,000 attendees.

Ru graduated with a degree in Finance at the Georgetown University McDonough School of Business in 2007. He and two other co-Founded Sweetgreen, and he serves as one of the company’s Co-Chief Executive Officer’s. Ru has stated the the signature moment of Sweetgreen came about when they opened a location in Dupont Circle near Washington D.C. and no one showed up for the first two weeks of business. He and the others came up with the idea of playing music outside the store on the weekends which finally garnered the customers they needed.

 

 

 The GoFundMe Initiative

Renowned dentist and philanthropist Dr. Avi WeisFogel launched his GoFundMe campaign for Operation Smile to help fund cost-free surgical solutions to kids and Young adults suffering from cleft lips and cleft palate and other similar deformities.

Operation Smile is a charity organization that provides aesthetic Dental Services to underprivileged Patients globally. The organization was founded in 1982 by Kathy and Bill. Their first mission was to help children in Philippines though over time they have established themselves globally.They conduct medical missions all over the world and sometimes import equipment or medical expertise based on circumstances available. Through kind, generous donations like Dr. Weisfogels, Operation Smile can make the world a better place.

GoFundMe is a fundraising platform that allows anyone to raise funds for various uses or causes. As a dedicated philanthropist, Dr. Weisfogel consistently donates to a range of charities; he is helpful to hundreds, if not thousands, of kids worldwide in receiving life changing surgery which they could never have received. This GoFundMe drive targets to raise $2,000 so as to aid the free services offered by Operation Smile to children and young adults.

Avi Weisfogel’s goal is to lend a hand in the dutiful work that Operation Smile provides so that children in the entire world receive treatment regardless of their conditions, that is comparable to that which they would receive if they belonged to us. The money raised from the GoFundme campaign will be used in necessary medical equipment acquisition and handling and hiring of medical professionals that carry out these operations.

The organization has a lucid purpose that is valuable worldwide especially to kids. Dr. Avi Weisfogel decision to raise money for Operation Smile is apparent since it is in line with his passion for humanity. Avi Weisfogel views this campaign as an ideal way to give hopeless kids another chance of having a brighter future. Operation Smile goals are in order with Avi Weisfogel passion of providing the best care for children.

How to Get Out of Your Own Way and Succeed in Life and Business

Let’s have a closer look at the ways I which a young person can succeed in life and business using the guidelines set by Josh Verne.

 

  1. Everything must be a win-win

In business, leaders should never fall prey of acceding business deals which never have a closing end in mind. For this reason, they end up accepting deals which are one sided to benefit only themselves. If you are such a leader, it just a matter of time before your business starts swinging with numerous problems. For you to succeed in life and business, you much choose to negotiate bends which allow you to have a win-win situation.

 

If you win in business, your clients will also win. In the end, you will have everyone including the business community and society win because you have all people winning. There is always a way to have a win created for everyone in any business deal. It is for you to figure out the ways in which you can twist the deal to benefit all people. When you stop laying your focus on deals which have no benefit for all people, you will be faced with situations which make you accede to the business deals. Whenever you are faced with a deal, ensure it has everyone included for the benefit. In this way, you and your company will figure out the right way to skyrocket.

 

  1. Listen more, speak less

This is the most profound point of all. A normal human being has two ears and one mouth. Therefore, he must strive to use these organs in their correct form. While you speak once, ensure you listen twice as much as you speak. For this reason, you will have more power in whatever you speak. People will tend to trust your words because they believe you have carefully thought about the before speaking.

 

Brazilian Investment Adviser Igor Cornelsen Explains Types of Diversification

You might have heard of the value of financial “diversification.” This is a great way for you to handle downturns in the market. If you lose some money, a diversified portfolio will not fall all the way down to zero. Brazilian stock investment businessman Igor Cornelsen explains the various types of diversification.

“Asset Type”

The “Rule of 100” is a common investing tool to help you gauge the balance of stocks and bonds in your wealth portfolio. Basically, you subtract your age to determine the percentage of stocks, you should have in your portfolio.

As you age, you might want more conservative investments, like bonds. Mr. Igor Cornelsen can help you balance the asset types in your portfolio. This can help you handle any severe changes in the economy.

“Risk Tolerance”

Each investor has his own “risk tolerance.” This means the “amount of risk you can handle with an investment.” Certain stocks will have a much more dramatic range of prices when they are trading. If you can handle risk, you might like more energy, bio-technology, Internet and startup firms.

Derivatives also are rated based on their risk characteristics. A mortgage backed security (MBS) will have certain tranches aimed at certain types of investors. Some rental properties might have more irregular revenue streams on icrowdnewswire.com. You can discuss your risk tolerance with Mr. Cornelsen and find the ideal financial product.

Read more: Igor Cornelsen gives you the basics on Brazilian banking

“Country & Currency”

In the modern investing climate, geographical investment diversity is also quite important. As an expert in Brazilian banking, Mr. Igor Cornelsen can help you find good financial products in the country . This allows you to handle any crises in one particular nation.

A good example is the Brexit vote on Lulu. Before the vote, some Brits were selling their pounds for euros. If you already had some investments in other countries, you would be well-protected.

Asset values go “up-and-down” – diversification smooths over these rough spots. When you find the ideal asset mix, you can prepare for any exigency. You should also work with your wealth adviser Igor Cornelsen to modify the mix each year to better reflect your needs.

Getting Reliable Legal Advice and Representation in Brazil

Are you in need of a good legal adviser in Brazil? Need a lawyer who is well versed in litigation? If you find yourself dealing with a legal issue, whether it’s a business related concern or personal challenge, it’s imperative that you get appropriate representation. A competent legal counsel in Brazil can help you navigate the complicated legal process and advise you about the best way to address the case.

A quick search online will return numerous results, presenting you with websites of legal practitioners in Brazil. Keep in mind that not all legal counsels you find this way will be right for your situation. It is vital to search for one that is well experienced in the type of case you are dealing with.

A good legal adviser in Brazil can advise you about all the required paperwork and documentation to support your case, and they know Brazilian’s court procedures and rules, and they can address any issues or critical questions you may have about the legal process along the way.

Once you have found some lawyer or attorneys who might be right for you, the next step is to schedule a consultation so you can learn more about them before making a decision. During your meeting with an attorney, you will have a chance to present your concerns or ask any questions you may have.

To ensure that you get a good law firm or attorney for your case, it might be advisable to write down important information. Take notes as you review or discuss about your case so that you can evaluate the material later. Before you ultimately make a decision on which legal adviser you would like to choose, you can compare the answers you get during the meeting.

It is crucial to retain the services of an attorney who will aggressively defend you, to get you the most beneficial outcome in your dispute. That’s where Ricardo Tosto de Oliveira Carvalho comes in.

Ricardo Tosto is well known for providing powerful representation in all matters related to business and corporate law. His clients include large companies, corporations, entrepreneurs, institutions and individuals who need legal advice from a top rated lawyer. Ricardo Tosto has a great reputation in the legal arena and comes highly recommended.

Ricardo Tosto is a remarkable legal professional in Brazil, with over 22 years of experience in Brazilian Law. He is known for his special ability to design and apply effective strategies and to give his clients 100 % attention in their matter. He has great litigation and negotiation skills, and many of his clients are extremely satisfied with his performance and the outcome in their case.

How A Dynamic Salad Chain Is Taking Over Fast Food

Modern food beckons for quickness, affordability, and most importantly, health. As exemplified by chains like Chipotle, natural, locally-sourced meals sell en masse. After a couple of statistical studies, even McDonalds has revamped their ingredients. However, the new buzz is the sexiest startup of recent memory, Sweetgreen. An avant-garde salad-shop, no one could have predicted that this start-up would sweep the west coast. Now, locations have sprung up from Boston to New York, exemplifying the flexibility of the shop. The best part of this “VC darling” success story is the man at the helm. Nathaniel Ru, a 3-month graduate, led this business to the sharp status it possesses.

 

When picturing a green salad, most people would not imagine a main course, especially not a filling one, talk about being hard to market. Yet, a team of three graduates employing some start-up capital (from the likes of AOL co-founder Danny Meyer) somehow made salad sexy. However, the businesses golden status does not simply come from the elegant posturing of its quaint salad shoppes.

 

Nathaniel Ru has spread his influence throughout the company, and is based in robust interpersonal relations. As any great leader, he understands that people work in unique synergy when they feel a team atmosphere. It is part of humanity’s tribal nature. Thus, supervisors at Sweetgreen are “Coaches”, and employees are “team members”. Furthermore, Ru makes sure that relations with local farmers are tight. To this capacity, he has found unique solutions to food-waste problems. Ensuring a green, carbon neutral image.

 

Ru keeps it fresh, Sweetgreen even holds an annual music festival with legit performers. Headliners from Calvin Harris to The Weeknd certainly do not hurt Sweetgreen’s image. The event has over 20,000 attendees, so anyone that is hip will be there. Quite the social engineer, Ru has a clever way of entering markets, and dominating them. He times his entry into various markets through sequencing to maximize popularity and efficiency. It must work, as he over 27 locations in 6 states. Keeping in touch with brand identity, Ru maintains minimalist elegance, reminiscent of apple stores. This keeps the atmosphere consistent and modern across the board. Of course, the store has an app (used by about 30% of customers), which ensures a meal for time-sensitive busy-bodies.

 

In today’s age of scientific advances, people understand the need to break the cycle of fast-food chemical festivals. Indeed, the unprecedented success of this salad-chain symbolizes America’s changing demographic. Although burger-cravings are sure keep stalwarts in the market, Sweetgreen’s country-wide success is a serious indicator of changing trends. In more tangible terms, a consistently fresh salad which constitutes a true meal is huge shift from previous conventions.