Oncotarget Reports Incredible Prostate Cancer News

Prostate cancer affects millions of men every year and is one of the deadliest if not caught quickly. Thankfully, it can be easily treated if it is caught quickly enough, but what baffles many researchers is why this cancer recurs after it has been treated.

A new study by Roswell Park, as reported by Oncotarget, indicates new hope in helping those who suffer from this problem. So if you or a loved one is suffering from prostate cancer and needs a little hope in a difficult time, read on to find out how treatment may be affected.

Read more articles at ImpactJournals.com.

The Standard Treatment Method

Before discussing the Roswell Park study, it is a good idea to understand the way prostate cancer is typically treated. Generally, it is treated by blocking androgen production in men. This male sex hormone is the main cause of prostate cancer and blocking it typically stops it from recurring after the treatment method is over.

However, it is possible for prostate cancer to recur even with this treatment method. Thankfully, it doesn’t occur regularly enough to be a major threat to the health of most men. But it occurs in enough to make it important to find a way to stop it. And Roswell Park may have taken the first step in the right direction.

Their Findings

The incredible breakthroughs reported by Roswell Park found that there is actually an 11-gene signature in recurring cancer tumors that is not prevalent in non-recurring prostate cancer. This major breakthrough makes it possible to test these tumors ahead of time to get a feel for the chance of recurring tumors.

This finding also helps support the idea that it is possible to combine various forms of treatment to combat this problem. Being able to identify potentially recurring tumors earlier in the process will make it possible to use this therapy method earlier and eliminate the chance of rampant recurring tumors.

The importance of this finding cannot be overstated. It could potentially change the way prostate cancer is treated and could even work as a potential cure. Read all about it in the latest issue of Oncotarget to get an idea of what to expect.

Also read journals at DovePress.com.

Mike Baur Advances Support To Startups Through The Swiss Startup Factory

Mike Baur, since 2014, has been working with startups in the IT industry by offering them the needed support to advance to achieve their potential. His initiative that is fueled through the Swiss Startup Factory has helped many startups that held great potential to manifest themselves in the right manner. He launched the Swiss Startup Factory in 2014 and has been working through a three months incubation program that allows selected startups to enjoy mentorship and funding that is meant to usher them into the complex world of business.

 

He quit being a banker to venture into business and entrepreneurship and it seems his ideas have worked in favor of his expectations. The success Mike Baur has earned all along is as a result of the great support he has received from other successful professionals in the industry.

 

Business development

Although many entrepreneurs come with smart ideas, they lack special skills that can help them to develop their ideas into sustainable businesses. Many of those who fail to get the support of experts fail just few months into inception. These are some of the things the Swiss Startup Factory is working to eliminate by availing experts to support the young entrepreneurs through advice and guidance. To enhance the effectiveness of the program, the Swiss Startup Factory has also partnered with universities across the country to ensure there is sufficient supply of the needed materials. The business development support is handled in the accelerator phase of the incubation program.

 

Access to funding

Once the idea is verified to be unique and capable of expanding to offer great results, those who lack the funds to push the business to the next level are presented before investors, who also happen to be professionals capable of offering advice about the management of the business. The entrepreneur pitches and if the idea is selected, they are offered funding to run the business through its inception. The Swiss Startup Factory is availing many tools and openings for young entrepreneurs to make their ideas a reality.

 

Post accelerator support

The post accelerator support is offered after the three months incubation period elapses. This is necessary to ensure all the ideas that were shared during the incubation phase are included in the running of the company. Additionally, the entrepreneur may not be in a position to implement a perfect strategy, so professional support is needed to correct some mistakes before they escalate to disaster.

PodcastOne Debuts Exhilarating Show that Shines a Light on Paranormal Mysteries

Exploring the paranormal has always been a bone of contention to many. However, leading podcast network, PodcastOne, announced a new show called “Beyond the Darkness” that is poised to identify truths from lies. The show will be hosted on WWE Superstar Chris Jericho’s podcast network. Beyond the Darkness explores supernatural mysteries and will feature stimulating conversations with prominent researchers in the field and testimonies from people who have experienced real life encounters.

 

The podcast will not only enlighten and entertain but also challenge viewers’ perception on matters concerning ghouls, demons, monsters, aliens, angels, and ghosts. Dave Schrader, radio host and author, alongside radio producer Tim Dennis, will host the show. New episodes are set to be released via PodcastOne.com, i-Tunes, and the PodcastOne phone application every Monday.

 

During the announcement, Mr. Pattiz, Founder of PodcastOne, stated that Chris Jericho had stood out during his time at PodcastOne Network. He added that when Chris started The Jericho Network Collection, he had high hopes that it would grow beyond wrestling.

 

Speaking about the podcast, Chris Jericho expressed his excitement and slight chills towards the show, set to air on The Jericho Network (an affiliate of PodcastOne). He added that the hosts; Tim and Dave, already enjoy a huge following and will be instrumental in helping the show attract a huge fan base.

 

PodcastOne’s Profile

 

Norman Pattiz founded PodcastOne after leaving Westwood One. Under his leadership, the podcast grew to become a highly respected podcast network in America. The network hosts over 200 popular podcasts such as Dr. Drew, The Forbes on PodcastOne Network, Steve Austin, Dan Patrick, Eddie Trunk, Adam Corolla, Penn Jillette, Jay Mohr, Ross Mathews, Shaquille O’Neal, Gabrielle Reece, Rich Eisen, TheCHIVE, Chris Webber, and Neil Strauss.

https://podcastone.com/About-Us

Norman Pattiz

 

Mr. Pattiz established Westwood One, which is now the largest American radio network and distributor of entertainment, sports, news, and traffic programming. He later launched PodcastOne, which encompassed a variety of shows, and PodcastOne Sales, which focuses on marketing and sales to raise revenue. After his appointment in 2002 by President Bill Clinton, Mr. Pattiz joined the Broadcasting Board of Governors and was reappointed in 2002 by President Bush.

 

Mr. Pattiz is a proud National Radio Hall of Famer. The Library of American Broadcasting also awarded him with the Giants of Broadcasting Award. He Chairs the Los Alamos and Lawrence Livermore National Security Laboratories and serves as a University of California Regent.

Follow Pattiz on LinkedIn

JeanMarie Guenot And Amphivena Therapeutics: Chasing The Cure For Cancer

 

It has been an exciting year for Amphivena Threrapeutics. The company developed several promising advances in cancer immunotherapies. One of the most notable of these is AMV564, the company’s proprietary T-cell redirecting bispecific CD33/CD3 antibody. The United States Fod and Drug Administration accepted the investigational drug and it will began to be given to Leukemia patients.

 

While AMV564 is only in phase one of the investigational process, Jeanmarie Guenot, Ph.D., the president and chief executive officer of Amphivena Therapeutics (http://amphivena.com/amphivena_leaders/jeanmarie-guenot-ph-d/), is positive that it will bring promising news to the pharmaceutical industry. She believes that this first phase will open several new treatment options for medical professionals and cancer patients.

 

“Our preclinical program demonstrated impressive cytotoxic activity in AML patient samples and animal models that was both potent and selective,” Guenot explained. “This is suggesting the potential for a robust therapeutic response with minimal off-target safety concerns.”

 

Guenot looks forward to beginning the clinical phase of testing and is optimistic about the future of Amphivena Therapeutics. The company believes that this therapy treatment has huge potential to change the way cancer is approached.

 

JeanMarie Guenot further explains on her personal Facebook, that AMV564 aims to eliminate cancer cells in the body, including the bine, marrow and blood. If phase one goes as plan, AMV564 could be headed to clinical trials very soon.

 

Guenot is no stranger to this industry. In fact, she has more than twenty years in the pharmaceutical and biotechnology industry. Her leadership of the San Francisco based, Amphivena Therapeutics has been a highlight of her career. With such promising advancement being made, Guenot and Amphivena Therapeutics have been featured by several major news outlets, such as BusinessWire.

 

The future looks extremely bright for this successful oncology startup company whose mission is to eliminate the presence of blood cancers and provided a cure to those it has affected.  Jeanmarie Guenot and Amphivena announced a partnership with Takeda to continue their medical work.

 

The Story of SweetGreen

The story of Sweetgreen begins with Nathaniel Ru and his friends having trouble finding healthy places to eat while in college. In addition to healthy they were looking for restaurants that were “fun and easy”. To this end they took particular interest in a nearby tavern which they transformed into the founding location of the Sweetgreen chain of restaurants.

Six years later, they had rebuilt the tavern, located in Washington D.C., into a 21-store-farm-to-table restaurant. The landlord of the building that the tavern was located in had doubts about their plans, but eventually they were able to convince her to lease the location to them. From that one location Sweetgreen has now expanded to restaurants across the nation including the states of New York, Massachusetts, Pennsylvania, and the greater Washington D.C. area.

The food that the company uses mostly comes from local farmers around each restaurant location. In addition to offering food, Sweetgreen’s Head of Digital Marketing Theresa Dold has stated that the company was started with a “deeper purpose”. This purpose was for Sweetgreen to answer the question of “why”. She went on to say that they want to be local, smart, sexy, and social and by the way we sell a great line of juices and have a music festival every year.

Nathaniel Ru has stated that every restaurant they open has to live up to their five core values which includes serving the local community around it. The core values include “win, win, win” where everyone has a stake, sustainability, “keeping it real” where everything is authentic, “sweet” which means creating meaningful connections between farmers, Sweetgreen, and customers, and making a positive impact.

As the company wants to connect food and music, they came up with a food & musical festival that they called Sweetlife. Sweetlife has evolved into the areas largest music and food festival, with as many as 20,000 attendees.

Ru graduated with a degree in Finance at the Georgetown University McDonough School of Business in 2007. He and two other co-Founded Sweetgreen, and he serves as one of the company’s Co-Chief Executive Officer’s. Ru has stated the the signature moment of Sweetgreen came about when they opened a location in Dupont Circle near Washington D.C. and no one showed up for the first two weeks of business. He and the others came up with the idea of playing music outside the store on the weekends which finally garnered the customers they needed.

 

 

 The GoFundMe Initiative

Renowned dentist and philanthropist Dr. Avi WeisFogel launched his GoFundMe campaign for Operation Smile to help fund cost-free surgical solutions to kids and Young adults suffering from cleft lips and cleft palate and other similar deformities.

Operation Smile is a charity organization that provides aesthetic Dental Services to underprivileged Patients globally. The organization was founded in 1982 by Kathy and Bill. Their first mission was to help children in Philippines though over time they have established themselves globally.They conduct medical missions all over the world and sometimes import equipment or medical expertise based on circumstances available. Through kind, generous donations like Dr. Weisfogels, Operation Smile can make the world a better place.

GoFundMe is a fundraising platform that allows anyone to raise funds for various uses or causes. As a dedicated philanthropist, Dr. Weisfogel consistently donates to a range of charities; he is helpful to hundreds, if not thousands, of kids worldwide in receiving life changing surgery which they could never have received. This GoFundMe drive targets to raise $2,000 so as to aid the free services offered by Operation Smile to children and young adults.

Avi Weisfogel’s goal is to lend a hand in the dutiful work that Operation Smile provides so that children in the entire world receive treatment regardless of their conditions, that is comparable to that which they would receive if they belonged to us. The money raised from the GoFundme campaign will be used in necessary medical equipment acquisition and handling and hiring of medical professionals that carry out these operations.

The organization has a lucid purpose that is valuable worldwide especially to kids. Dr. Avi Weisfogel decision to raise money for Operation Smile is apparent since it is in line with his passion for humanity. Avi Weisfogel views this campaign as an ideal way to give hopeless kids another chance of having a brighter future. Operation Smile goals are in order with Avi Weisfogel passion of providing the best care for children.

How to Get Out of Your Own Way and Succeed in Life and Business

Let’s have a closer look at the ways I which a young person can succeed in life and business using the guidelines set by Josh Verne.

 

  1. Everything must be a win-win

In business, leaders should never fall prey of acceding business deals which never have a closing end in mind. For this reason, they end up accepting deals which are one sided to benefit only themselves. If you are such a leader, it just a matter of time before your business starts swinging with numerous problems. For you to succeed in life and business, you much choose to negotiate bends which allow you to have a win-win situation.

 

If you win in business, your clients will also win. In the end, you will have everyone including the business community and society win because you have all people winning. There is always a way to have a win created for everyone in any business deal. It is for you to figure out the ways in which you can twist the deal to benefit all people. When you stop laying your focus on deals which have no benefit for all people, you will be faced with situations which make you accede to the business deals. Whenever you are faced with a deal, ensure it has everyone included for the benefit. In this way, you and your company will figure out the right way to skyrocket.

 

  1. Listen more, speak less

This is the most profound point of all. A normal human being has two ears and one mouth. Therefore, he must strive to use these organs in their correct form. While you speak once, ensure you listen twice as much as you speak. For this reason, you will have more power in whatever you speak. People will tend to trust your words because they believe you have carefully thought about the before speaking.

 

Brazilian Investment Adviser Igor Cornelsen Explains Types of Diversification

You might have heard of the value of financial “diversification.” This is a great way for you to handle downturns in the market. If you lose some money, a diversified portfolio will not fall all the way down to zero. Brazilian stock investment businessman Igor Cornelsen explains the various types of diversification.

“Asset Type”

The “Rule of 100” is a common investing tool to help you gauge the balance of stocks and bonds in your wealth portfolio. Basically, you subtract your age to determine the percentage of stocks, you should have in your portfolio.

As you age, you might want more conservative investments, like bonds. Mr. Igor Cornelsen can help you balance the asset types in your portfolio. This can help you handle any severe changes in the economy.

“Risk Tolerance”

Each investor has his own “risk tolerance.” This means the “amount of risk you can handle with an investment.” Certain stocks will have a much more dramatic range of prices when they are trading. If you can handle risk, you might like more energy, bio-technology, Internet and startup firms.

Derivatives also are rated based on their risk characteristics. A mortgage backed security (MBS) will have certain tranches aimed at certain types of investors. Some rental properties might have more irregular revenue streams on icrowdnewswire.com. You can discuss your risk tolerance with Mr. Cornelsen and find the ideal financial product.

Read more: Igor Cornelsen gives you the basics on Brazilian banking

“Country & Currency”

In the modern investing climate, geographical investment diversity is also quite important. As an expert in Brazilian banking, Mr. Igor Cornelsen can help you find good financial products in the country . This allows you to handle any crises in one particular nation.

A good example is the Brexit vote on Lulu. Before the vote, some Brits were selling their pounds for euros. If you already had some investments in other countries, you would be well-protected.

Asset values go “up-and-down” – diversification smooths over these rough spots. When you find the ideal asset mix, you can prepare for any exigency. You should also work with your wealth adviser Igor Cornelsen to modify the mix each year to better reflect your needs.

Getting Reliable Legal Advice and Representation in Brazil

Are you in need of a good legal adviser in Brazil? Need a lawyer who is well versed in litigation? If you find yourself dealing with a legal issue, whether it’s a business related concern or personal challenge, it’s imperative that you get appropriate representation. A competent legal counsel in Brazil can help you navigate the complicated legal process and advise you about the best way to address the case.

A quick search online will return numerous results, presenting you with websites of legal practitioners in Brazil. Keep in mind that not all legal counsels you find this way will be right for your situation. It is vital to search for one that is well experienced in the type of case you are dealing with.

A good legal adviser in Brazil can advise you about all the required paperwork and documentation to support your case, and they know Brazilian’s court procedures and rules, and they can address any issues or critical questions you may have about the legal process along the way.

Once you have found some lawyer or attorneys who might be right for you, the next step is to schedule a consultation so you can learn more about them before making a decision. During your meeting with an attorney, you will have a chance to present your concerns or ask any questions you may have.

To ensure that you get a good law firm or attorney for your case, it might be advisable to write down important information. Take notes as you review or discuss about your case so that you can evaluate the material later. Before you ultimately make a decision on which legal adviser you would like to choose, you can compare the answers you get during the meeting.

It is crucial to retain the services of an attorney who will aggressively defend you, to get you the most beneficial outcome in your dispute. That’s where Ricardo Tosto de Oliveira Carvalho comes in.

Ricardo Tosto is well known for providing powerful representation in all matters related to business and corporate law. His clients include large companies, corporations, entrepreneurs, institutions and individuals who need legal advice from a top rated lawyer. Ricardo Tosto has a great reputation in the legal arena and comes highly recommended.

Ricardo Tosto is a remarkable legal professional in Brazil, with over 22 years of experience in Brazilian Law. He is known for his special ability to design and apply effective strategies and to give his clients 100 % attention in their matter. He has great litigation and negotiation skills, and many of his clients are extremely satisfied with his performance and the outcome in their case.

How A Dynamic Salad Chain Is Taking Over Fast Food

Modern food beckons for quickness, affordability, and most importantly, health. As exemplified by chains like Chipotle, natural, locally-sourced meals sell en masse. After a couple of statistical studies, even McDonalds has revamped their ingredients. However, the new buzz is the sexiest startup of recent memory, Sweetgreen. An avant-garde salad-shop, no one could have predicted that this start-up would sweep the west coast. Now, locations have sprung up from Boston to New York, exemplifying the flexibility of the shop. The best part of this “VC darling” success story is the man at the helm. Nathaniel Ru, a 3-month graduate, led this business to the sharp status it possesses.

 

When picturing a green salad, most people would not imagine a main course, especially not a filling one, talk about being hard to market. Yet, a team of three graduates employing some start-up capital (from the likes of AOL co-founder Danny Meyer) somehow made salad sexy. However, the businesses golden status does not simply come from the elegant posturing of its quaint salad shoppes.

 

Nathaniel Ru has spread his influence throughout the company, and is based in robust interpersonal relations. As any great leader, he understands that people work in unique synergy when they feel a team atmosphere. It is part of humanity’s tribal nature. Thus, supervisors at Sweetgreen are “Coaches”, and employees are “team members”. Furthermore, Ru makes sure that relations with local farmers are tight. To this capacity, he has found unique solutions to food-waste problems. Ensuring a green, carbon neutral image.

 

Ru keeps it fresh, Sweetgreen even holds an annual music festival with legit performers. Headliners from Calvin Harris to The Weeknd certainly do not hurt Sweetgreen’s image. The event has over 20,000 attendees, so anyone that is hip will be there. Quite the social engineer, Ru has a clever way of entering markets, and dominating them. He times his entry into various markets through sequencing to maximize popularity and efficiency. It must work, as he over 27 locations in 6 states. Keeping in touch with brand identity, Ru maintains minimalist elegance, reminiscent of apple stores. This keeps the atmosphere consistent and modern across the board. Of course, the store has an app (used by about 30% of customers), which ensures a meal for time-sensitive busy-bodies.

 

In today’s age of scientific advances, people understand the need to break the cycle of fast-food chemical festivals. Indeed, the unprecedented success of this salad-chain symbolizes America’s changing demographic. Although burger-cravings are sure keep stalwarts in the market, Sweetgreen’s country-wide success is a serious indicator of changing trends. In more tangible terms, a consistently fresh salad which constitutes a true meal is huge shift from previous conventions.